Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells

Accumulating evidence indicates that the senescence-associated secretory phenotype (SASP) contributes to many aspects of physiology and disease. Thus, controlling the SASP will have tremendous impacts on our health. However, our understanding of SASP regulation is far from complete. Here, we show th...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Takahashi, Akiko, Loo, Tze Mun, Okada, Ryo, Kamachi, Fumitaka, Watanabe, Yoshihiro, Wakita, Masahiro, Watanabe, Sugiko, Kawamoto, Shimpei, Miyata, Kenichi, Barber, Glen N., Ohtani, Naoko, Hara, Eiji
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871854/
https://ncbi.nlm.nih.gov/pubmed/29593264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03555-8
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker