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Impact of senescence‐associated secretory phenotype and its potential as a therapeutic target for senescence‐associated diseases

“Cellular senescence” is a state in which cells undergo irreversible cell cycle arrest in response to a variety of cellular stresses. Once cells senesce, they are strongly resistant to any mitogens, including oncogenic stimuli. Therefore, cellular senescence has been assumed to be a potent anticance...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Watanabe, Sugiko, Kawamoto, Shimpei, Ohtani, Naoko, Hara, Eiji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406532/
https://ncbi.nlm.nih.gov/pubmed/28165648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13184
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