S-Adenosyl-L-Homocysteine Hydrolase Inhibition by a Synthetic Nicotinamide Cofactor Biomimetic

S-adenosyl-L-homocysteine (SAH) hydrolases (SAHases) are involved in the regulation of methylation reactions in many organisms and are thus crucial for numerous cellular functions. Consequently, their dysregulation is associated with severe health problems. The SAHase-catalyzed reaction is reversibl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Kailing, Lyn L., Bertinetti, Daniela, Paul, Caroline E., Manszewski, Tomasz, Jaskolski, Mariusz, Herberg, Friedrich W., Pavlidis, Ioannis V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871694/
https://ncbi.nlm.nih.gov/pubmed/29619018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00505
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge