Llwytho...

Metal-cation regulation of enzyme dynamics is a key factor influencing the activity of S-adenosyl-l-homocysteine hydrolase from Pseudomonas aeruginosa

S-adenosyl-l-homocysteine hydrolase from Pseudomonas aeruginosa (PaSAHase) coordinates one K(+) ion and one Zn(2+) ion in the substrate binding area. The cations affect the enzymatic activity and substrate binding but the molecular mechanisms of their action are unknown. Enzymatic and isothermal tit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Czyrko, Justyna, Sliwiak, Joanna, Imiolczyk, Barbara, Gdaniec, Zofia, Jaskolski, Mariusz, Brzezinski, Krzysztof
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063907/
https://ncbi.nlm.nih.gov/pubmed/30054521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29535-y
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