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S-adenosyl-L-homocysteine hydrolase from a hyperthermophile (Thermotoga maritima) is expressed in Escherichia coli in inactive form – Biochemical and structural studies

Thermotoga maritima is a hyperthermophilic bacterium but its genome encodes a number of archaeal proteins including S-adenosyl-L-homocysteine hydrolase (SAHase), which regulates cellular methylation reactions. The question of proper folding and activity of proteins of extremophilic origin is an intr...

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Detalhes bibliográficos
Publicado no:Int J Biol Macromol
Main Authors: Brzezinski, Krzysztof, Czyrko, Justyna, Sliwiak, Joanna, Nalewajko-Sieliwoniuk, Edyta, Jaskolski, Mariusz, Nocek, Boguslaw, Dauter, Zbigniew
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7888557/
https://ncbi.nlm.nih.gov/pubmed/28629859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijbiomac.2017.06.065
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