Development of a repeat-exposure penile SHIV infection model in macaques to evaluate biomedical preventions against HIV

Penile acquisition of HIV infection contributes substantially to the global epidemic. Our goal was to establish a preclinical macaque model of penile HIV infection for evaluating the efficacy of new HIV prevention modalities. Rhesus macaques were challenged once or twice weekly with consistent doses...

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Bibliographic Details
Published in:PLoS One
Main Authors: Garber, David A., Mitchell, James, Adams, Debra, Guenthner, Patricia, Deyounks, Frank, Ellis, Shanon, Kelley, Kristen, Johnson, Ryan, Dobard, Charles, Heneine, Walid, McNicholl, Janet
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870976/
https://ncbi.nlm.nih.gov/pubmed/29584769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194837
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