Susceptibility to Repeated, Low-Dose, Rectal SHIV(SF162P3) Challenge Is Independent of TRIM5 Genotype in Rhesus Macaques

Infections following repeated, low-dose (RLD), mucal S(H)IV exposures of macaques are used to model sexual HIV exposures for biomedical prevention testing. Different susceptibilities among animals can complicate study designs. In rhesus macaques, TRIM5 alleles Q, CypA, and TFP are resistance factors...

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Dettagli Bibliografici
Autori principali: Butler, Katherine, Morgan, Jennifer S., Hanson, Debra L., Adams, Debra, Garcia-Lerma, J. Gerardo, Heneine, Walid, Ellenberger, Dennis, Hendry, R. Michael, McNicholl, Janet, Johnson, Welkin E., Kersh, Ellen N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2013
Soggetti:
Virology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685693/
https://ncbi.nlm.nih.gov/pubmed/23461569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0383
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