Susceptibility to Repeated, Low-Dose, Rectal SHIV(SF162P3) Challenge Is Independent of TRIM5 Genotype in Rhesus Macaques

Infections following repeated, low-dose (RLD), mucal S(H)IV exposures of macaques are used to model sexual HIV exposures for biomedical prevention testing. Different susceptibilities among animals can complicate study designs. In rhesus macaques, TRIM5 alleles Q, CypA, and TFP are resistance factors...

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Detalles Bibliográficos
Autores principales: Butler, Katherine, Morgan, Jennifer S., Hanson, Debra L., Adams, Debra, Garcia-Lerma, J. Gerardo, Heneine, Walid, Ellenberger, Dennis, Hendry, R. Michael, McNicholl, Janet, Johnson, Welkin E., Kersh, Ellen N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2013
Materias:
Virology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685693/
https://ncbi.nlm.nih.gov/pubmed/23461569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0383
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