Short Communication: Practical Experience with Analysis and Design of Repeat Low-Dose SHIV(SF162P3) Exposure Studies in Female Pigtail Macaques with Varying Susceptibility During Menstrual Cycling

Vaginal SHIV(SF162P3) acquisition in pigtail macaques (Macaca nemestrina) is dependent on time point during the menstrual cycle. Susceptibility is higher around menstruation and lower at ovulation in mid cycle. This complicates the design of repeat low-dose (RLD) SHIV exposure studies because virus...

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Enregistré dans:
Détails bibliographiques
Publié dans:AIDS Res Hum Retroviruses
Auteurs principaux: Kersh, Ellen N., Henning, Tara R., Dobard, Charles, Heneine, Walid, McNicholl, Janet M.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2015
Sujets:
Outcomes Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636932/
https://ncbi.nlm.nih.gov/pubmed/26165400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2014.0373
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