Repeated vaginal SHIV challenges in macaques receiving oral or topical Pre-Exposure Prophylaxis induce virus-specific T cell responses

BACKGROUND: Pre-Exposure Prophylaxis (PrEP) for HIV prevention is a novel biomedical prevention method. We have previously modeled PrEP during rectal SHIV exposures in macaques and identified that SHIV-specific T cell responses were induced in the presence of antiretroviral drugs, an observation pre...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: Tsegaye, Theodros Solomon, Butler, Katherine, Luo, Wei, Radzio, Jessica, Srinivasan, Priya, Sharma, Sunita, Aubert, Rachael D., Hanson, Debra L., Dobard, Charles, Garcia-Lerma, J. Gerardo, Heneine, Walid, McNicholl, Janet M., Kersh, Ellen N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485592/
https://ncbi.nlm.nih.gov/pubmed/25886925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000642
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