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DNA sequence+shape kernel enables alignment-free modeling of transcription factor binding
MOTIVATION: Transcription factors (TFs) bind to specific DNA sequence motifs. Several lines of evidence suggest that TF-DNA binding is mediated in part by properties of the local DNA shape: the width of the minor groove, the relative orientations of adjacent base pairs, etc. Several methods have bee...
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| Vydáno v: | Bioinformatics |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5870879/ https://ncbi.nlm.nih.gov/pubmed/28541376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx336 |
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