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Reliability of algorithmic somatic copy number alteration detection from targeted capture data

MOTIVATION: Whole exome and gene panel sequencing are increasingly used for oncological diagnostics. To investigate the accuracy of SCNA detection algorithms on simulated and clinical tumor samples, the precision and sensitivity of four SCNA callers were measured using 50 simulated whole exome and 5...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Rieber, Nora, Bohnert, Regina, Ziehm, Ulrike, Jansen, Gunther
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870863/
https://ncbi.nlm.nih.gov/pubmed/28472276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx284
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