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Reliability of algorithmic somatic copy number alteration detection from targeted capture data

MOTIVATION: Whole exome and gene panel sequencing are increasingly used for oncological diagnostics. To investigate the accuracy of SCNA detection algorithms on simulated and clinical tumor samples, the precision and sensitivity of four SCNA callers were measured using 50 simulated whole exome and 5...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Bioinformatics
मुख्य लेखकों: Rieber, Nora, Bohnert, Regina, Ziehm, Ulrike, Jansen, Gunther
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870863/
https://ncbi.nlm.nih.gov/pubmed/28472276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx284
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