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Reliability of algorithmic somatic copy number alteration detection from targeted capture data
MOTIVATION: Whole exome and gene panel sequencing are increasingly used for oncological diagnostics. To investigate the accuracy of SCNA detection algorithms on simulated and clinical tumor samples, the precision and sensitivity of four SCNA callers were measured using 50 simulated whole exome and 5...
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| Udgivet i: | Bioinformatics |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5870863/ https://ncbi.nlm.nih.gov/pubmed/28472276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx284 |
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