Delphinidin induced protective autophagy via mTOR pathway suppression and AMPK pathway activation in HER-2 positive breast cancer cells

BACKGROUND: We have previously demonstrated the anticancer effect of anthocyanins. In this study, we explored the biological activities of delphinidin, the most common of the anthocyanidin monomers, that were related to autophagy in HER-2 positive breast cancer MDA-MB-453 and BT474 cells. METHODS: T...

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Publicado en:BMC Cancer
Autores principales: Chen, Jingyao, Zhu, Yanfeng, Zhang, Weiwei, Peng, Xiaoli, Zhou, Jie, Li, Fei, Han, Bin, Liu, Xin, Ou, Yu, Yu, Xiaoping
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870693/
https://ncbi.nlm.nih.gov/pubmed/29587684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4231-y
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