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Delphinidin induced protective autophagy via mTOR pathway suppression and AMPK pathway activation in HER-2 positive breast cancer cells

BACKGROUND: We have previously demonstrated the anticancer effect of anthocyanins. In this study, we explored the biological activities of delphinidin, the most common of the anthocyanidin monomers, that were related to autophagy in HER-2 positive breast cancer MDA-MB-453 and BT474 cells. METHODS: T...

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Publicat a:BMC Cancer
Autors principals: Chen, Jingyao, Zhu, Yanfeng, Zhang, Weiwei, Peng, Xiaoli, Zhou, Jie, Li, Fei, Han, Bin, Liu, Xin, Ou, Yu, Yu, Xiaoping
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870693/
https://ncbi.nlm.nih.gov/pubmed/29587684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4231-y
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