popFBA: tackling intratumour heterogeneity with Flux Balance Analysis

MOTIVATION: Intratumour heterogeneity poses many challenges to the treatment of cancer. Unfortunately, the transcriptional and metabolic information retrieved by currently available computational and experimental techniques portrays the average behaviour of intermixed and heterogeneous cell subpopul...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Damiani, Chiara, Di Filippo, Marzia, Pescini, Dario, Maspero, Davide, Colombo, Riccardo, Mauri, Giancarlo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Ismb/Eccb 2017: The 25th Annual Conference Intelligent Systems for Molecular Biology Held Jointly with the 16th Annual European Conference on Computational Biology, Prague, Czech Republic, July 21–25, 2017
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870635/
https://ncbi.nlm.nih.gov/pubmed/28881985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx251
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