popFBA: tackling intratumour heterogeneity with Flux Balance Analysis

MOTIVATION: Intratumour heterogeneity poses many challenges to the treatment of cancer. Unfortunately, the transcriptional and metabolic information retrieved by currently available computational and experimental techniques portrays the average behaviour of intermixed and heterogeneous cell subpopul...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioinformatics
Prif Awduron: Damiani, Chiara, Di Filippo, Marzia, Pescini, Dario, Maspero, Davide, Colombo, Riccardo, Mauri, Giancarlo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Ismb/Eccb 2017: The 25th Annual Conference Intelligent Systems for Molecular Biology Held Jointly with the 16th Annual European Conference on Computational Biology, Prague, Czech Republic, July 21–25, 2017
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870635/
https://ncbi.nlm.nih.gov/pubmed/28881985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx251
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