popFBA: tackling intratumour heterogeneity with Flux Balance Analysis

MOTIVATION: Intratumour heterogeneity poses many challenges to the treatment of cancer. Unfortunately, the transcriptional and metabolic information retrieved by currently available computational and experimental techniques portrays the average behaviour of intermixed and heterogeneous cell subpopul...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Damiani, Chiara, Di Filippo, Marzia, Pescini, Dario, Maspero, Davide, Colombo, Riccardo, Mauri, Giancarlo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Ismb/Eccb 2017: The 25th Annual Conference Intelligent Systems for Molecular Biology Held Jointly with the 16th Annual European Conference on Computational Biology, Prague, Czech Republic, July 21–25, 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870635/
https://ncbi.nlm.nih.gov/pubmed/28881985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx251
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