Implication of 4E-BP1 protein dephosphorylation and accumulation in pancreatic cancer cell death induced by combined gemcitabine and TRAIL

Pancreatic cancer cells show varying sensitivity to the anticancer effects of gemcitabine. However, as a chemotherapeutic agent, gemcitabine can cause intolerably high levels of toxicity and patients often develop resistance to the beneficial effects of this drug. Combination studies show that use o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Dis
Egile Nagusiak: Elia, Androulla, Henry-Grant, Ricky, Adiseshiah, Charlotte, Marboeuf, Catherine, Buckley, Rebecca J, Clemens, Michael J, Mudan, Satvinder, Pyronnet, Stéphane
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870593/
https://ncbi.nlm.nih.gov/pubmed/29233971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0001-z
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