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Quantitative profiling of BATF family proteins/JUNB/IRF hetero-trimers using Spec-seq

BACKGROUND: BATF family transcription factors (BATF, BATF2 and BATF3) form hetero-trimers with JUNB and either IRF4 or IRF8 to regulate cell fate in T cells and dendritic cells in vivo. While each combination of the hetero-trimer has a distinct role, some degree of cross-compensation was observed. T...

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Udgivet i:BMC Mol Biol
Main Authors: Chang, Yiming K., Zuo, Zheng, Stormo, Gary D.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869772/
https://ncbi.nlm.nih.gov/pubmed/29587652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-018-0106-7
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