Antagonism between the transcription factors NANOG and OTX2 specifies rostral or caudal cell fate during neural patterning transition

During neurogenesis, neural patterning is a critical step during which neural progenitor cells differentiate into neurons with distinct functions. However, the molecular determinants that regulate neural patterning remain poorly understood. Here we optimized the “dual SMAD inhibition” method to spec...

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發表在:J Biol Chem
Main Authors: Su, Zhenghui, Zhang, Yanqi, Liao, Baojian, Zhong, Xiaofen, Chen, Xin, Wang, Haitao, Guo, Yiping, Shan, Yongli, Wang, Lihui, Pan, Guangjin
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2018
主題:
Cell Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868256/
https://ncbi.nlm.nih.gov/pubmed/29386354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.815449
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