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Self-patterning of rostral-caudal neuroectoderm requires dual role of Fgf signaling for localized Wnt antagonism

The neuroectoderm is patterned along a rostral-caudal axis in response to localized factors in the embryo, but exactly how these factors act as positional information for this patterning is not yet fully understood. Here, using the self-organizing properties of mouse embryonic stem cell (ESC), we re...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Takata, Nozomu, Sakakura, Eriko, Eiraku, Mototsugu, Kasukawa, Takeya, Sasai, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673904/
https://ncbi.nlm.nih.gov/pubmed/29109536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01105-2
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