The anti-tumor effects of dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A on inducing autophagy in esophageal squamous cell carcinoma

The effect and regulation of autophagy-related proteins Beclin-1 and LC3 in esophageal squamous cell carcinoma have not been fully studied. The aim of this study was to assess the expression of Beclin-1 and LC3 in ESCCs, and to investigate the association between the two markers and clinicopathologi...

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Publicado en:J Cancer
Autores principales: Wu, Ning, Zhu, Yingfeng, Xu, Xiao, Zhu, Yongjun, Song, Yang, Pang, Liewen, Chen, Zhiming
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2018
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868166/
https://ncbi.nlm.nih.gov/pubmed/29581778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.22861
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