Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens

Studying human hepatotropic pathogens such as hepatitis B and C viruses and malaria will be necessary for understanding host-pathogen interactions, and developing therapy and prophylaxis. Unfortunately, existing in vitro liver models typically employ either cell lines that exhibit aberrant physiolog...

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Veröffentlicht in:Nat Protoc
Hauptverfasser: March, Sandra, Ramanan, Vyas, Trehan, Kartik, Ng, Shengyong, Galstian, Ani, Gural, Nil, Scull, Margaret A., Shlomai, Amir, Mota, Maria, Fleming, Heather E., Khetani, Salman R., Rice, Charles M., Bhatia, Sangeeta N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867906/
https://ncbi.nlm.nih.gov/pubmed/26584444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2015.128
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