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Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro

Homeostasis of mammalian cell function strictly depends on balancing oxygen exposure to maintain energy metabolism without producing excessive reactive oxygen species. In vivo, cells in different tissues are exposed to a wide range of oxygen concentrations, and yet in vitro models almost exclusively...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ng, Shengyong, March, Sandra, Galstian, Ani, Hanson, Kirsten, Carvalho, Tânia, Mota, Maria M., Bhatia, Sangeeta N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Limited 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917242/
https://ncbi.nlm.nih.gov/pubmed/24291761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.013490
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