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Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro

Homeostasis of mammalian cell function strictly depends on balancing oxygen exposure to maintain energy metabolism without producing excessive reactive oxygen species. In vivo, cells in different tissues are exposed to a wide range of oxygen concentrations, and yet in vitro models almost exclusively...

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Detalhes bibliográficos
Main Authors: Ng, Shengyong, March, Sandra, Galstian, Ani, Hanson, Kirsten, Carvalho, Tânia, Mota, Maria M., Bhatia, Sangeeta N.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917242/
https://ncbi.nlm.nih.gov/pubmed/24291761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.013490
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