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Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro

Homeostasis of mammalian cell function strictly depends on balancing oxygen exposure to maintain energy metabolism without producing excessive reactive oxygen species. In vivo, cells in different tissues are exposed to a wide range of oxygen concentrations, and yet in vitro models almost exclusively...

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Bibliografische gegevens
Hoofdauteurs: Ng, Shengyong, March, Sandra, Galstian, Ani, Hanson, Kirsten, Carvalho, Tânia, Mota, Maria M., Bhatia, Sangeeta N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Limited 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917242/
https://ncbi.nlm.nih.gov/pubmed/24291761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.013490
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