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Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro

Homeostasis of mammalian cell function strictly depends on balancing oxygen exposure to maintain energy metabolism without producing excessive reactive oxygen species. In vivo, cells in different tissues are exposed to a wide range of oxygen concentrations, and yet in vitro models almost exclusively...

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Dettagli Bibliografici
Autori principali: Ng, Shengyong, March, Sandra, Galstian, Ani, Hanson, Kirsten, Carvalho, Tânia, Mota, Maria M., Bhatia, Sangeeta N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Limited 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917242/
https://ncbi.nlm.nih.gov/pubmed/24291761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.013490
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