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Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers

The malaria liver stage is an attractive target for antimalarial development, and preclinical malaria models are essential for testing such candidates. Given ethical concerns and costs associated with non‐human primate models, humanized mouse models containing chimeric human livers offer a valuable...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ng, Shengyong, March, Sandra, Galstian, Ani, Gural, Nil, Stevens, Kelly R., Mota, Maria M., Bhatia, Sangeeta N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374446/
https://ncbi.nlm.nih.gov/pubmed/28361899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45424
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