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In Vitro Alterations Do Not Reflect a Requirement for Host Cell Cycle Progression during Plasmodium Liver Stage Infection

Prior to invading nonreplicative erythrocytes, Plasmodium parasites undergo their first obligate step in the mammalian host inside hepatocytes, where each sporozoite replicates to generate thousands of merozoites. While normally quiescent, hepatocytes retain proliferative capacity and can readily re...

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Bibliografiske detaljer
Udgivet i:Eukaryot Cell
Main Authors: Hanson, Kirsten K., March, Sandra, Ng, Shengyong, Bhatia, Sangeeta N., Mota, Maria M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279013/
https://ncbi.nlm.nih.gov/pubmed/25416236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00166-14
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