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In Vitro Alterations Do Not Reflect a Requirement for Host Cell Cycle Progression during Plasmodium Liver Stage Infection

Prior to invading nonreplicative erythrocytes, Plasmodium parasites undergo their first obligate step in the mammalian host inside hepatocytes, where each sporozoite replicates to generate thousands of merozoites. While normally quiescent, hepatocytes retain proliferative capacity and can readily re...

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Detalhes bibliográficos
Publicado no:Eukaryot Cell
Main Authors: Hanson, Kirsten K., March, Sandra, Ng, Shengyong, Bhatia, Sangeeta N., Mota, Maria M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279013/
https://ncbi.nlm.nih.gov/pubmed/25416236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00166-14
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