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Micropatterned Co-Cultures of Human Hepatocytes and Stromal Cells for the Assessment of Drug Clearance and Drug-Drug Interactions
Drug clearance rates from the body can determine drug exposure that can affect efficacy and/or toxicity. Thus, accurate prediction of drug clearance during preclinical development can help guide dose selection in humans; however, animal testing is not always predictive of human outcomes. Since hepat...
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| Publicat a: | Curr Protoc Toxicol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495000/ https://ncbi.nlm.nih.gov/pubmed/28463419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptx.23 |
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