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Human hepatocyte assessment of imatinib drug–drug interactions – complexities in clinical translation
AIM: Inducers and inhibitors of CYP3A, such as ritonavir and efavirenz, may be used as part of the highly active antiretroviral therapy (HAART) to treat HIV patients. HIV patients with chronic myeloid leukemia or gastrointestinal stromal tumour may need imatinib, a CYP3A4 substrate with known exposu...
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| Publicado en: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631182/ https://ncbi.nlm.nih.gov/pubmed/26178713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12723 |
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