Human hepatocyte assessment of imatinib drug–drug interactions – complexities in clinical translation

AIM: Inducers and inhibitors of CYP3A, such as ritonavir and efavirenz, may be used as part of the highly active antiretroviral therapy (HAART) to treat HIV patients. HIV patients with chronic myeloid leukemia or gastrointestinal stromal tumour may need imatinib, a CYP3A4 substrate with known exposu...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Br J Clin Pharmacol
Glavni autori: Beumer, Jan H, Pillai, Venkateswaran C, Parise, Robert A, Christner, Susan M, Kiesel, Brian F, Rudek, Michelle A, Venkataramanan, Raman
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
Teme:
Drug Interactions
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631182/
https://ncbi.nlm.nih.gov/pubmed/26178713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12723
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items