Cargando...

Physiologically Inspired Culture Medium Prolongs the Lifetime and Insulin Sensitivity of Human Hepatocytes in Micropatterned Co-cultures

Given significant species-specific differences in liver functions, cultures of primary human hepatocytes (PHHs) are useful for assessing drug metabolism and to mitigate the risk of drug-induced hepatotoxicity in humans. While significant advances have been made to keep PHHs highly functional for 2–4...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Toxicology
Main Authors: Davidson, Matthew D., Pickrell, Joshua, Khetani, Salman R.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855998/
https://ncbi.nlm.nih.gov/pubmed/33359713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2020.152662
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!