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Interleukin-10 promotes primary rat hepatic stellate cell senescence by upregulating the expression levels of p53 and p21
Liver fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) components, and activated hepatic stellate cells (HSCs) are a primary source of ECM. Several studies have revealed that the induction of HSC senescence may reduce liver fibrosis. The effect of interleukin-10 (I...
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| Publicat a: | Mol Med Rep |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
D.A. Spandidos
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5866012/ https://ncbi.nlm.nih.gov/pubmed/29436649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8592 |
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