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Interleukin-10 promotes primary rat hepatic stellate cell senescence by upregulating the expression levels of p53 and p21

Liver fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) components, and activated hepatic stellate cells (HSCs) are a primary source of ECM. Several studies have revealed that the induction of HSC senescence may reduce liver fibrosis. The effect of interleukin-10 (I...

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Podrobná bibliografie
Vydáno v:Mol Med Rep
Hlavní autoři: Huang, Yue-Hong, Chen, Ming-Hua, Guo, Qi-Lan, Chen, Yun-Xin, Zhang, Li-Juan, Chen, Zhi-Xin, Wang, Xiao-Zhong
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866012/
https://ncbi.nlm.nih.gov/pubmed/29436649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8592
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