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Lysyl oxidase inhibition via β-aminoproprionitrile hampers human umbilical vein endothelial cell angiogenesis and migration in vitro

Lysyl oxidase (LOX) is an enzyme that oxidizes lysine residues in collagens and elastin. It stabilizes or remodels the extracellular matrix and basement membrane of blood vessels. Current oncology studies have revealed that LOX is upregulated in invasive cancer cells and bolstered cell movement, and...

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Bibliografiske detaljer
Udgivet i:Mol Med Rep
Main Authors: Shi, Lin, Zhang, Ning, Liu, Hetao, Zhao, Lei, Liu, Jing, Wan, Juan, Wu, Wenyi, Lei, Hetian, Liu, Rongqing, Han, Mei
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865964/
https://ncbi.nlm.nih.gov/pubmed/29393489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8508
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