Lysyl oxidase inhibition via β-aminoproprionitrile hampers human umbilical vein endothelial cell angiogenesis and migration in vitro

Lysyl oxidase (LOX) is an enzyme that oxidizes lysine residues in collagens and elastin. It stabilizes or remodels the extracellular matrix and basement membrane of blood vessels. Current oncology studies have revealed that LOX is upregulated in invasive cancer cells and bolstered cell movement, and...

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Publicat a:Mol Med Rep
Autors principals: Shi, Lin, Zhang, Ning, Liu, Hetao, Zhao, Lei, Liu, Jing, Wan, Juan, Wu, Wenyi, Lei, Hetian, Liu, Rongqing, Han, Mei
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2018
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865964/
https://ncbi.nlm.nih.gov/pubmed/29393489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8508
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