Growth Factors Outside of the Platelet-derived Growth Factor (PDGF) Family Employ Reactive Oxygen Species/Src Family Kinases to Activate PDGF Receptor α and Thereby Promote Proli...

by Lei, Hetian, Kazlauskas, Andrius
Published 2009

Focus on Molecules: Platelet-derived Growth Factor C, PDGF-C

by Lei, Hetian, Kazlauskas, Andrius
Published 2007

A Reactive Oxygen Species-Mediated, Self-Perpetuating Loop Persistently Activates Platelet-Derived Growth Factor Receptor α

by Lei, Hetian, Kazlauskas, Andrius
Published 2014

Pathological Signaling via Platelet-Derived Growth Factor Receptor α Involves Chronic Activation of Akt and Suppression of p53

by Lei, Hetian, Velez, Gisela, Kazlauskas, Andrius
Published 2011

Recent developments in our understanding of how platelet-derived growth factor (PDGF) and its receptors contribute to proliferative vitreoretinopathy

by Lei, Hetian, Rheaume, Marc-Andre, Kazlauskas, Andrius
Published 2009

Plasmin Is the Major Protease Responsible for Processing PDGF-C in the Vitreous of Patients with Proliferative Vitreoretinopathy

by Lei, Hetian, Velez, Gisela, Hovland, Peter, Hirose, Tatsuo, Kazlauskas, Andrius
Published 2008

THE ALPHA RECEPTOR FOR PLATELET DERIVED GROWTH FACTOR CONFERS BONE-METASTATIC POTENTIAL TO PROSTATE CANCER CELLS BY LIGAND- AND DIMERIZATION-INDEPENDENT MECHANISMS

by Russell, Mike R., Liu, Qingxin, Lei, Hetian, Kazlauskas, Andrius, Fatatis, Alessandro
Published 2010

Expression of PDGFRα Is a Determinant of the PVR Potential of ARPE19 Cells

by Lei, Hetian, Rhéaume, Marc-André, Velez, Gisela, Mukai, Shizuo, Kazlauskas, Andrius
Published 2011

SU9518 Inhibits Proliferative Vitreoretinopathy in Fibroblast and Genetically Modified Müller Cell–Induced Rabbit Models

by Velez, Gisela, Weingarden, Alexa R., Lei, Hetian, Kazlauskas, Andrius, Gao, Guangping
Published 2013

Growth Factors Outside the PDGF Family Drive Experimental PVR

by Lei, Hetian, Velez, Gisela, Hovland, Peter, Hirose, Tatsuo, Gilbertson, Debra, Kazlauskas, Andrius
Published 2009

Phosphoinositide 3-kinase δ inactivation prevents vitreous-induced activation of AKT/MDM2/p53 and migration of retinal pigment epithelial cells

by Han, Haote, Chen, Na, Huang, Xionggao, Liu, Bing, Tian, Jingkui, Lei, Hetian
Published in J Biol Chem (2019)

Correction: Phosphoinositide 3-kinase δ inactivation prevents vitreous-induced activation of AKT/MDM2/p53 and migration of retinal pigment epithelial cells.

by Han, Haote, Chen, Na, Huang, Xionggao, Liu, Bing, Tian, Jingkui, Lei, Hetian
Published in J Biol Chem (2019)

PDGF Receptor-α Does Not Promote HCMV Entry into Epithelial and Endothelial Cells but Increased Quantities Stimulate Entry by an Abnormal Pathway

by Vanarsdall, Adam L., Wisner, Todd W., Lei, Hetian, Kazlauskas, Andrius, Johnson, David C.
Published 2012

PDGF Receptors Are Activated in Human Epiretinal Membranes

by Cui, Jing, Lei, Hetian, Samad, Arif, Basavanthappa, Sreenivasa, Maberley, David, Matsubara, Joanne, Kazlauskas, Andrius
Published 2008

N-Acetylcysteine Suppresses Retinal Detachment in an Experimental Model of Proliferative Vitreoretinopathy

by Lei, Hetian, Velez, Gisela, Cui, Jing, Samad, Arif, Maberley, David, Matsubara, Joanne, Kazlauskas, Andrius
Published 2010

RasGAP Promotes Autophagy and Thereby Suppresses Platelet-Derived Growth Factor Receptor-Mediated Signaling Events, Cellular Responses, and Pathology

by Lei, Hetian, Qian, Cynthia X., Lei, Jinghu, Haddock, Luis J., Mukai, Shizuo, Kazlauskas, Andrius
Published in Mol Cell Biol (2015)

The Clustered, Regularly Interspaced, Short Palindromic Repeats-associated Endonuclease 9 (CRISPR/Cas9)-created MDM2 T309G Mutation Enhances Vitreous-induced Expression of MDM2 and...

by Duan, Yajian, Ma, Gaoen, Huang, Xionggao, D'Amore, Patricia A., Zhang, Feng, Lei, Hetian
Published in J Biol Chem (2016)

Retinal Pigment Epithelium and Müller Progenitor Cell Interaction Increase Müller Progenitor Cell Expression of PDGFRα and Ability to Induce Proliferative Vitreoretinopathy in a Ra...

by Velez, Gisela, Weingarden, Alexa R., Tucker, Budd A., Lei, Hetian, Kazlauskas, Andrius, Young, Michael J.
Published 2012

Editing VEGFR2 Blocks VEGF-Induced Activation of Akt and Tube Formation

by Huang, Xionggao, Zhou, Guohong, Wu, Wenyi, Ma, Gaoen, D'Amore, Patricia A., Mukai, Shizuo, Lei, Hetian
Published in Invest Ophthalmol Vis Sci (2017)

A Novel Function of p53: A Gatekeeper of Retinal Detachment

by Lei, Hetian, Rheaume, Marc-Andre, Cui, Jing, Mukai, Shizuo, Maberley, David, Samad, Arif, Matsubara, Joanne, Kazlauskas, Andrius
Published 2012