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Editing VEGFR2 Blocks VEGF-Induced Activation of Akt and Tube Formation
PURPOSE: Vascular endothelial growth factor receptor 2 (VEGFR2) plays a key role in VEGF-induced angiogenesis. The goal of this project was to test the hypothesis that editing genomic VEGFR2 loci using the technology of clustered regularly interspaced palindromic repeats (CRISPR)-associated DNA endo...
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| Publicado no: | Invest Ophthalmol Vis Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338630/ https://ncbi.nlm.nih.gov/pubmed/28241310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20537 |
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