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Posttransplant chimeric antigen receptor therapy

Therapeutic T-cell engineering is emerging as a powerful approach to treat refractory hematological malignancies. Its most successful embodiment to date is based on the use of second-generation chimeric antigen receptors (CARs) targeting CD19, a cell surface molecule found in most B-cell leukemias a...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Smith, Melody, Zakrzewski, Johannes, James, Scott, Sadelain, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865610/
https://ncbi.nlm.nih.gov/pubmed/29358181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-752121
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