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The DNA methylation profile of liver tumors in C3H mice and identification of differentially methylated regions involved in the regulation of tumorigenic genes

BACKGROUND: C3H mice have been frequently used in cancer studies as animal models of spontaneous liver tumors and chemically induced hepatocellular carcinoma (HCC). Epigenetic modifications, including DNA methylation, are among pivotal control mechanisms of gene expression leading to carcinogenesis....

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Detaylı Bibliyografya
Yayımlandı:BMC Cancer
Asıl Yazarlar: Matsushita, Junya, Okamura, Kazuyuki, Nakabayashi, Kazuhiko, Suzuki, Takehiro, Horibe, Yu, Kawai, Tomoko, Sakurai, Toshihiro, Yamashita, Satoshi, Higami, Yoshikazu, Ichihara, Gaku, Hata, Kenichiro, Nohara, Keiko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865360/
https://ncbi.nlm.nih.gov/pubmed/29566670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4221-0
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