YM155 decreases radiation-induced invasion and reverses epithelial–mesenchymal transition by targeting STAT3 in glioblastoma

BACKGROUND: Radiotherapy constitutes a standard arm of therapy in the multimodal treatment of patients with glioblastoma (GBM). Ironically, studies have recently revealed that radiation can augment malignant progression, by promoting migration and invasion, which make the disease especially difficul...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Transl Med
मुख्य लेखकों: Zhang, Xin, Wang, Xuehai, Xu, Ran, Ji, Jianxiong, Xu, Yangyang, Han, Mingzhi, Wei, Yuzhen, Huang, Bin, Chen, Anjing, Zhang, Qing, Li, Wenjie, Wang, Jian, Li, Xingang, Qiu, Chen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2018
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865331/
https://ncbi.nlm.nih.gov/pubmed/29571296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1451-5
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