YM155 decreases radiation-induced invasion and reverses epithelial–mesenchymal transition by targeting STAT3 in glioblastoma

BACKGROUND: Radiotherapy constitutes a standard arm of therapy in the multimodal treatment of patients with glioblastoma (GBM). Ironically, studies have recently revealed that radiation can augment malignant progression, by promoting migration and invasion, which make the disease especially difficul...

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Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: Zhang, Xin, Wang, Xuehai, Xu, Ran, Ji, Jianxiong, Xu, Yangyang, Han, Mingzhi, Wei, Yuzhen, Huang, Bin, Chen, Anjing, Zhang, Qing, Li, Wenjie, Wang, Jian, Li, Xingang, Qiu, Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865331/
https://ncbi.nlm.nih.gov/pubmed/29571296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1451-5
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