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Structure and evolution of the Fam20 kinases
The Fam20 proteins are novel kinases that phosphorylate secreted proteins and proteoglycans. Fam20C phosphorylates hundreds of secreted proteins and is activated by the pseudokinase Fam20A. Fam20B phosphorylates a xylose residue to regulate proteoglycan synthesis. Despite these wide-ranging and impo...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5865150/ https://ncbi.nlm.nih.gov/pubmed/29572475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03615-z |
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