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Structure and evolution of the Fam20 kinases

The Fam20 proteins are novel kinases that phosphorylate secreted proteins and proteoglycans. Fam20C phosphorylates hundreds of secreted proteins and is activated by the pseudokinase Fam20A. Fam20B phosphorylates a xylose residue to regulate proteoglycan synthesis. Despite these wide-ranging and impo...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Zhang, Hui, Zhu, Qinyu, Cui, Jixin, Wang, Yuxin, Chen, Mark J., Guo, Xing, Tagliabracci, Vincent S., Dixon, Jack E., Xiao, Junyu
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865150/
https://ncbi.nlm.nih.gov/pubmed/29572475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03615-z
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