Structure and evolution of the Fam20 kinases

The Fam20 proteins are novel kinases that phosphorylate secreted proteins and proteoglycans. Fam20C phosphorylates hundreds of secreted proteins and is activated by the pseudokinase Fam20A. Fam20B phosphorylates a xylose residue to regulate proteoglycan synthesis. Despite these wide-ranging and impo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Zhang, Hui, Zhu, Qinyu, Cui, Jixin, Wang, Yuxin, Chen, Mark J., Guo, Xing, Tagliabracci, Vincent S., Dixon, Jack E., Xiao, Junyu
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865150/
https://ncbi.nlm.nih.gov/pubmed/29572475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03615-z
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