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Structure and evolution of the Fam20 kinases

The Fam20 proteins are novel kinases that phosphorylate secreted proteins and proteoglycans. Fam20C phosphorylates hundreds of secreted proteins and is activated by the pseudokinase Fam20A. Fam20B phosphorylates a xylose residue to regulate proteoglycan synthesis. Despite these wide-ranging and impo...

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Publicat a:Nat Commun
Autors principals: Zhang, Hui, Zhu, Qinyu, Cui, Jixin, Wang, Yuxin, Chen, Mark J., Guo, Xing, Tagliabracci, Vincent S., Dixon, Jack E., Xiao, Junyu
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865150/
https://ncbi.nlm.nih.gov/pubmed/29572475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03615-z
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