Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging

Chronic obstructive pulmonary disease (COPD) has been recently characterized as a disease of accelerated lung aging, but the mechanism remains unclear. Tetraspanins have emerged as key players in malignancy and inflammatory diseases. Here, we found that CD9/CD81 double knockout (DKO) mice with a COP...

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Publicado en:Sci Rep
Autores principales: Jin, Yingji, Takeda, Yoshito, Kondo, Yasushi, Tripathi, Lokesh P., Kang, Sujin, Takeshita, Hikari, Kuhara, Hanako, Maeda, Yohei, Higashiguchi, Masayoshi, Miyake, Kotaro, Morimura, Osamu, Koba, Taro, Hayama, Yoshitomo, Koyama, Shohei, Nakanishi, Kaori, Iwasaki, Takeo, Tetsumoto, Satoshi, Tsujino, Kazuyuki, Kuroyama, Muneyoshi, Iwahori, Kota, Hirata, Haruhiko, Takimoto, Takayuki, Suzuki, Mayumi, Nagatomo, Izumi, Sugimoto, Ken, Fujii, Yuta, Kida, Hiroshi, Mizuguchi, Kenji, Ito, Mari, Kijima, Takashi, Rakugi, Hiromi, Mekada, Eisuke, Tachibana, Isao, Kumanogoh, Atsushi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865149/
https://ncbi.nlm.nih.gov/pubmed/29572511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23338-x
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