Rapid intracranial response to osimertinib, without radiotherapy, in nonsmall cell lung cancer patients harboring the EGFR T790M mutation: Two Case Reports

RATIONALE: Most of nonsmall cell lung cancer (NSCLC) patients harboring epidermal growth factor receptor (EGFR) activating mutations eventually acquire resistance to the first EGFR-tyrosine kinase inhibitors (TKIs) therapy after varying periods of treatment. Of note, approximately one-third of those...

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Bibliographic Details
Published in:Medicine (Baltimore)
Main Authors: Koba, Taro, Kijima, Takashi, Takimoto, Takayuki, Hirata, Haruhiko, Naito, Yujiro, Hamaguchi, Masanari, Otsuka, Tomoyuki, Kuroyama, Muneyoshi, Nagatomo, Izumi, Takeda, Yoshito, Kida, Hiroshi, Kumanogoh, Atsushi
Format: Artigo
Language:Inglês
Published: Wolters Kluwer Health 2017
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5700
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313025/
https://ncbi.nlm.nih.gov/pubmed/28178168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000006087
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