Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging

Chronic obstructive pulmonary disease (COPD) has been recently characterized as a disease of accelerated lung aging, but the mechanism remains unclear. Tetraspanins have emerged as key players in malignancy and inflammatory diseases. Here, we found that CD9/CD81 double knockout (DKO) mice with a COP...

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Publicado no:Sci Rep
Main Authors: Jin, Yingji, Takeda, Yoshito, Kondo, Yasushi, Tripathi, Lokesh P., Kang, Sujin, Takeshita, Hikari, Kuhara, Hanako, Maeda, Yohei, Higashiguchi, Masayoshi, Miyake, Kotaro, Morimura, Osamu, Koba, Taro, Hayama, Yoshitomo, Koyama, Shohei, Nakanishi, Kaori, Iwasaki, Takeo, Tetsumoto, Satoshi, Tsujino, Kazuyuki, Kuroyama, Muneyoshi, Iwahori, Kota, Hirata, Haruhiko, Takimoto, Takayuki, Suzuki, Mayumi, Nagatomo, Izumi, Sugimoto, Ken, Fujii, Yuta, Kida, Hiroshi, Mizuguchi, Kenji, Ito, Mari, Kijima, Takashi, Rakugi, Hiromi, Mekada, Eisuke, Tachibana, Isao, Kumanogoh, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865149/
https://ncbi.nlm.nih.gov/pubmed/29572511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23338-x
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