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Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts
Iron is essential for growth and proliferation of mammalian cells. The maintenance of cellular iron homeostasis is regulated by iron regulatory proteins (IRPs) through binding to the cognate iron-responsive elements in target mRNAs and thereby regulating the expression of target genes. Irp1 or Irp2-...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5865113/ https://ncbi.nlm.nih.gov/pubmed/29572489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23175-y |
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