Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts

Iron is essential for growth and proliferation of mammalian cells. The maintenance of cellular iron homeostasis is regulated by iron regulatory proteins (IRPs) through binding to the cognate iron-responsive elements in target mRNAs and thereby regulating the expression of target genes. Irp1 or Irp2-...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Li, Huihui, Zhao, Hongting, Hao, Shuangying, Shang, Longcheng, Wu, Jing, Song, Chuanhui, Meyron-Holtz, Esther G., Qiao, Tong, Li, Kuanyu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865113/
https://ncbi.nlm.nih.gov/pubmed/29572489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23175-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items