GPVI signaling is compromised in newly formed platelets after acute thrombocytopenia in mice

At sites of vascular injury, exposed subendothelial collagens trigger platelet activation and thrombus formation by interacting with the immunoreceptor tyrosine-based activation motif (ITAM)–coupled glycoprotein VI (GPVI) on the platelet surface. Platelets are derived from the cytoplasm of megakaryo...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Gupta, Shuchi, Cherpokova, Deya, Spindler, Markus, Morowski, Martina, Bender, Markus, Nieswandt, Bernhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2018
Soggetti:
Platelets and Thrombopoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863702/
https://ncbi.nlm.nih.gov/pubmed/29295843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-800136
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi