GPVI signaling is compromised in newly formed platelets after acute thrombocytopenia in mice

At sites of vascular injury, exposed subendothelial collagens trigger platelet activation and thrombus formation by interacting with the immunoreceptor tyrosine-based activation motif (ITAM)–coupled glycoprotein VI (GPVI) on the platelet surface. Platelets are derived from the cytoplasm of megakaryo...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Gupta, Shuchi, Cherpokova, Deya, Spindler, Markus, Morowski, Martina, Bender, Markus, Nieswandt, Bernhard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2018
Konular:
Platelets and Thrombopoiesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863702/
https://ncbi.nlm.nih.gov/pubmed/29295843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-800136
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