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GPVI signaling is compromised in newly formed platelets after acute thrombocytopenia in mice
At sites of vascular injury, exposed subendothelial collagens trigger platelet activation and thrombus formation by interacting with the immunoreceptor tyrosine-based activation motif (ITAM)–coupled glycoprotein VI (GPVI) on the platelet surface. Platelets are derived from the cytoplasm of megakaryo...
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| Publicado no: | Blood |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5863702/ https://ncbi.nlm.nih.gov/pubmed/29295843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-800136 |
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