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NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling

Members of the NR4A subfamily of nuclear receptors have complex, overlapping roles during hematopoietic cell development and also function as tumor suppressors of hematologic malignancies. We previously identified NR4A1 and NR4A3 (NR4A1/3) as functionally redundant suppressors of acute myeloid leuke...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Freire, Pablo R., Conneely, Orla M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863701/
https://ncbi.nlm.nih.gov/pubmed/29343483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-795757
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